Effects of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor on respiratory burst activity of neutrophils in patients with myelodysplastic syndromes.

@article{Ohsaka1993EffectsOG,
  title={Effects of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor on respiratory burst activity of neutrophils in patients with myelodysplastic syndromes.},
  author={Akimichi Ohsaka and Seiichi Kitagawa and Akira Yuo and Kazuo Motoyoshi and Shinpei Furusawa and Yasusada Miura and Fumimaro Takaku and Mikiyoshi Saito},
  journal={Clinical and experimental immunology},
  year={1993},
  volume={91 2},
  pages={308-13}
}
The superoxide (O2-)-releasing capacity in response to N-formyl-methionyl-leucyl-phenylalanine (FMLP) and the priming effects of recombinant human granulocyte colony-stimulating factor (rhG-CSF) and granulocyte-macrophage colony-stimulating factor (rhGM-CSF) on FMLP-induced O2- release were investigated in neutrophils from 14 patients with myelodysplastic syndromes (MDS). The O2(-)-releasing capacity in MDS neutrophils varied from patient to patient. As compared with normal neutrophils, the O2… CONTINUE READING