Effects of graded reduction of brain blood flow on chemical control of breathing.

@article{Chapman1979EffectsOG,
  title={Effects of graded reduction of brain blood flow on chemical control of breathing.},
  author={Richard W. Chapman and Te{\'o}fila Santiago and Norman H. Edelman},
  journal={Journal of applied physiology: respiratory, environmental and exercise physiology},
  year={1979},
  volume={47 6},
  pages={1289-94}
}
We measured ventilatory responses to CO2 (delta VI/delta PCO2) and transient hypoxia (delta VI/delta SaO2) during reductions of brain blood flow (BBF) to 70% and 50% of control in unanesthetized goats. Increase in inspiratory volume per change in CO2 tension (delta VI/delta PCO2) was measured during rebreathing with sampling of both arterial and cerebral venous blood; increase in inspiratory volume per fall in arterial oxygen saturation (delta VI/delta SaO2) was assessed by the transient N2… CONTINUE READING

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