Effects of gonadotropins, insulin and insulin-like growth factor I on ovarian oxytocin and progesterone production.

Abstract

Oxytocin is produced in the granulosa-derived cells of the ruminant corpus luteum where its gene is dramatically up-regulated within days of ovulation. Regulation of these processes is poorly understood but oxytocin release can be increased by insulin, insulin-like growth factor I (IGF-I), and gonadotropins. Here we have assessed interactions between these… (More)

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