Effects of gonadectomy and testosterone replacement on growth hormone response to alpha 2 adrenergic stimulation in the male rat.

@article{Jansson1982EffectsOG,
  title={Effects of gonadectomy and testosterone replacement on growth hormone response to alpha 2 adrenergic stimulation in the male rat.},
  author={J O Jansson and Elias Eriksson and Staffan Ed{\'e}n and Kjell Modigh},
  journal={Psychoneuroendocrinology},
  year={1982},
  volume={7 2-3},
  pages={245-8}
}
The growth hormone (GH) response to clonidine in reserpine-pretreated rats is a putative in vivo model to reflect activation of central postsynaptic alpha 2 receptors. In the present study the influence of testosterone on the responsiveness of central alpha 2 receptors was investigated using this method. One week after operation the GH response to clonidine was drastically reduced in gonadectomized adult male rats compared to sham-operated controls. Testosterone replacement completely… CONTINUE READING