Effects of glutamate receptor activation on NG2-glia in the rat optic nerve.

@article{Hamilton2009EffectsOG,
  title={Effects of glutamate receptor activation on NG2-glia in the rat optic nerve.},
  author={Nicola Fox Hamilton and Paul S Hubbard and Arthur M Butt},
  journal={Journal of anatomy},
  year={2009},
  volume={214 2},
  pages={
          208-18
        }
}
NG2-glia are a substantial population of cells in the central nervous system (CNS) that can be identified by their specific expression of the NG2 chondroitin sulphate (CSPG). NG2-glia can generate oligodendrocytes, but it is unlikely this is their only function; indeed, they may be multipotent neural stem cells. Moreover, NG2-glia are a highly reactive cell type and a major function is to help form the axon growth inhibitory glial scar in response to CNS injury. The factors that regulate these… CONTINUE READING

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