Effects of gentamicin on sensorineural elements of the cochlea in human temporal bones.

@article{Kusunoki2004EffectsOG,
  title={Effects of gentamicin on sensorineural elements of the cochlea in human temporal bones.},
  author={Takeshi Kusunoki and Sebahattin Cureoglu and Patricia A. Schachern and Kazuyasu Baba and Shin Kariya and Andre Luis Lopes Sampaio and Michael Mauro Paparella},
  journal={American journal of otolaryngology},
  year={2004},
  volume={25 5},
  pages={313-7}
}
PURPOSE Gentamicin is commonly prescribed for treatment of gram-negative bacterial infections. It has, however, been known to have vestibulotoxic and ototoxic effects in humans. Previous studies were confounded by the use of other types of ototoxic drugs, higher than therapeutic doses, and prolonged time periods between gentamicin administration and death. The purpose of this study is to observe the effects of parenteral gentamicin administration on the sensorineural elements of the cochlea in… CONTINUE READING