Effects of general anaesthetic procedures on mitochondrial function of human skeletal muscle

@article{Mir1999EffectsOG,
  title={Effects of general anaesthetic procedures on mitochondrial function of human skeletal muscle},
  author={O Scar Mir{\'o} and Antonio Barrientos and J. R. Alonso and Jordi Casademont and D. Jarreta and {\'A}. Urbano-M{\'a}rquez and Francesc Cardellach},
  journal={European Journal of Clinical Pharmacology},
  year={1999},
  volume={55},
  pages={35-41}
}
Background: General anaesthetics inhibit mitochondrial function in animal models. However, very few studies have been performed in humans, and the results have not been conclusive. Methods: We prospectively studied the oxygen consumption and the individual enzyme activity of each complex of the mitochondrial respiratory chain of skeletal muscle mitochondria in 54 healthy individuals who underwent general anaesthesia for orthopaedic surgery. The control group (n = 54) was made up of individuals… CONTINUE READING
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[Effects of sedative agents on metabolic demand].

Annales francaises d'anesthesie et de reanimation • 2008
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 34 references

Biochemical and molecular investigations in respiratory chain deficiencies.

Clinica chimica acta; international journal of clinical chemistry • 1994
View 7 Excerpts
Highly Influenced

Reference charts for respiratory chain activities in human tissues.

Clinica chimica acta; international journal of clinical chemistry • 1994
View 4 Excerpts
Highly Influenced

General anesthetics. In: Goodman LS, Gilman A (eds). The pharmacological basis of therapeutics (8th edn)

BE Marshall, DE Longnecker
1990
View 4 Excerpts
Highly Influenced

E€ect of anesthetics on mitochondrial function

PJ Cohen
Anesthesiology • 1973
View 4 Excerpts
Highly Influenced

Muscular involvement in rheumatoid arthritis: clinico-pathological study of 21 symptomatic cases

O MiroÂ, E Pedrol, J Casademont
Semin Arthritis Rheum • 1996
View 1 Excerpt