Effects of gender difference on cardiac myocyte dysfunction in streptozotocin-induced diabetic rats

@article{Ding2007EffectsOG,
  title={Effects of gender difference on cardiac myocyte dysfunction in streptozotocin-induced diabetic rats},
  author={Yanfeng Ding and Ruijiao Zou and Robert L. Judd and Juming Zhong},
  journal={Endocrine},
  year={2007},
  volume={29},
  pages={135-141}
}
The main characteristics of type 1 diabetic cardiomyopathy include depressed contractility and altered electrophysiological properties in ventricular myocytes. The goal of the present study was to determine the potential influence of gender in the diabetes-induced pathogenesis of ventricular myocyte function. Diabetes in both male and female rats was induced by a single intravenous injection of streptozotocin (STZ). Diabetic rats exhibited hyperglycemia and reduced body weight gain in both male… Expand
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