Effects of gender difference on cardiac myocyte dysfunction in streptozotocin-induced diabetic rats
@article{Ding2007EffectsOG, title={Effects of gender difference on cardiac myocyte dysfunction in streptozotocin-induced diabetic rats}, author={Y. Ding and R. Zou and R. Judd and Juming Zhong}, journal={Endocrine}, year={2007}, volume={29}, pages={135-141} }
The main characteristics of type 1 diabetic cardiomyopathy include depressed contractility and altered electrophysiological properties in ventricular myocytes. The goal of the present study was to determine the potential influence of gender in the diabetes-induced pathogenesis of ventricular myocyte function. Diabetes in both male and female rats was induced by a single intravenous injection of streptozotocin (STZ). Diabetic rats exhibited hyperglycemia and reduced body weight gain in both male… CONTINUE READING
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