Effects of gemcitabine and gemcitabine in combination with carboplatin on five canine transitional cell carcinoma cell lines.

@article{Galvo2012EffectsOG,
  title={Effects of gemcitabine and gemcitabine in combination with carboplatin on five canine transitional cell carcinoma cell lines.},
  author={Joao Felipe de Brito Galv{\~a}o and William C. Kisseberth and Sridhar Murahari and Saikaew Sutayatram and Dennis J. Chew and Nongnuch Inpanbutr},
  journal={American journal of veterinary research},
  year={2012},
  volume={73 8},
  pages={1262-72}
}
OBJECTIVE To evaluate in vitro effects of gemcitabine alone and in combination with carboplatin on canine transitional cell carcinoma (TCC) cell lines. SAMPLE In vitro cultures of 5 canine TCC cell lines. PROCEDURES Cells were treated with gemcitabine, carboplatin, or a combination of both at various concentrations. Cell proliferation was assessed via a fluorescence-based microplate cell proliferation assay. Cell cycle was evaluated via propidium iodide staining, and apoptosis was assessed… CONTINUE READING
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