Effects of gastrin‐releasing peptide (GRP) on the mechanical activity of the human ileocaecal region in vitro

@article{Vadokas1997EffectsOG,
  title={Effects of gastrin‐releasing peptide (GRP) on the mechanical activity of the human ileocaecal region in vitro},
  author={B. Vadokas and F. E. L{\"u}dtke and G. Lepsien and K. Golenhofen and K. Mandrek},
  journal={Neurogastroenterology & Motility},
  year={1997},
  volume={9}
}
Mechanical activity was recorded in muscle preparations isolated from the human ileocaecal region. Gastrin‐releasing peptide (GRP, 10−9− 10−7 mol L−1) produced two types of response in the different muscle layers. Longitudinally cut strips showed a concentration‐dependent increase in the rhythmic activity, whereas the circularly orientated layers generally reacted with a small decrease in tone. These effects could not be influenced by blockade of adrenergic or cholinergic receptors or nerve… Expand
14 Citations
Gastrin-releasing peptides from Xenopus laevis: purification, characterization, and myotropic activity.
  • 7
  • PDF
Neurally mediated propagating discrete clustered contractions superimposed on myogenic ripples in ex vivo segments of human ileum.
  • 18
Generation of Spontaneous Tone by Gastrointestinal Sphincters.
  • 1
Colonic enteric nervous system analysis during parenteral nutrition.
  • 4
...
1
2
...

References

SHOWING 1-10 OF 23 REFERENCES
Characterization of bombesin effects on canine gastric muscle.
  • 51
Innervation of the muscularis mucosae of canine proximal colon.
  • 54
...
1
2
3
...