Effects of gamma aminobutyric acid (GABA) and muscimol on endocrine pancreatic function in man.

@article{Cavagnini1982EffectsOG,
  title={Effects of gamma aminobutyric acid (GABA) and muscimol on endocrine pancreatic function in man.},
  author={Francesco Cavagnini and Mirella Lo Pinto and Antonella Dubini and Cecilia Invitti and Graziella Cappelletti and Elio E. Polli},
  journal={Metabolism: clinical and experimental},
  year={1982},
  volume={31 1},
  pages={73-7}
}
The high concentrations of gamma aminobutyric acid (GABA) in the pancreatic islets and the neurotransmitter role played by this amino acid in the central nervous system, make it plausible that GABA also intervenes in the control of endocrine pancreatic function. In 12 normal subjects, a single oral dose of 5 or 10 g GABA, as compared to placebo, caused a significant (p less than 0.01) and dose-dependent (p less than 0.01) increase of plasma levels of immunoreactive insulin, C peptide and… CONTINUE READING