Effects of gabapentin on postoperative morphine consumption and pain after abdominal hysterectomy: a randomized, double-blind trial.

@article{Dierking2004EffectsOG,
  title={Effects of gabapentin on postoperative morphine consumption and pain after abdominal hysterectomy: a randomized, double-blind trial.},
  author={Gerd Dierking and Tina Hoff Duedahl and Michael L Rasmussen and Jonna Storm Fomsgaard and Steen M\oiniche and Janne R\omsing and J{\"o}rgen Dahl},
  journal={Acta anaesthesiologica Scandinavica},
  year={2004},
  volume={48 3},
  pages={322-7}
}
BACKGROUND Preliminary clinical studies have suggested that gabapentin may produce analgesia and reduce the need for opioids in postoperative patients. The aim of the present study was to investigate the opioid-sparing and analgesic effects of gabapentin administered during the first 24 h after abdominal hysterectomy. METHODS In a randomized, double-blind study, 80 patients received oral gabapentin 1200 mg or placebo 1 h before surgery, followed by oral gabapentin 600 mg or placebo 8, 16 and… CONTINUE READING

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