Effects of fusogenic agent on membrane structure of erythrocyte ghosts and the mechanism of membrane fusion

@article{Cullis1978EffectsOF,
  title={Effects of fusogenic agent on membrane structure of erythrocyte ghosts and the mechanism of membrane fusion},
  author={Pieter R Cullis and Michael J. Hope},
  journal={Nature},
  year={1978},
  volume={271},
  pages={672-674}
}
MEMBRANE fusion clearly requires that participating lipids assume some transitory non-bilayer configuration during the intermediate stages. Previous workers have suggested that intermediate micellar1 or inverted micellar2,3 structures may occur, but the precise nature of possible intermediates and their relation to the physical properties of membrane lipids are obscure. In this regard, Lucy and co-workers4–8 have shown that ‘fusogenic’ agents such as fatty acids and their derivatives induce… CONTINUE READING

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