Effects of forskolin on intracellular sodium activity in resting and stimulated cardiac Purkinje fibers from sheep.

In the present investigation, the effects of forskolin on intracellular sodium activity were studied in quiescent and electrically stimulated cardiac Purkinje fibers from sheep using Na+-sensitive microelectrodes. Also assessed, were the effects of this promoter of cytosolic cAMP production on resting membrane potential, action potential and twitch tension… CONTINUE READING