Effects of folic acid treatment on homocysteine levels and vascular disease in hemodialysis patients.

@article{Righetti2003EffectsOF,
  title={Effects of folic acid treatment on homocysteine levels and vascular disease in hemodialysis patients.},
  author={Marco Righetti and Gian M Ferrario and Silvana Milani and Paola Serbelloni and Lucia La Rosa and Mario Uccellini and Adalberto Sessa},
  journal={Medical science monitor : international medical journal of experimental and clinical research},
  year={2003},
  volume={9 4},
  pages={PI19-24}
}
BACKGROUND Cardiovascular disease is the most important cause of morbidity and mortality in hemodialysis patients. These patients frequently have hyperhomocysteinemia, a putative risk factor for cardiovascular disease. Treatment with folate, B6 and B12 partially reduces hyperhomocysteinemia. We conducted a long-term study to evaluate whether 15 mg is more effective than 5 mg oral folic acid as a daily dosage to decrease hyperhomocysteinemia, and to assess whether homocysteine-lowering treatment… CONTINUE READING
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