Effects of folic acid fortification on spina bifida prevalence in Brazil.

@article{Orioli2011EffectsOF,
  title={Effects of folic acid fortification on spina bifida prevalence in Brazil.},
  author={I{\^e}da M Orioli and Ricardo Lima do Nascimento and Jorge S L{\'o}pez-Camelo and Eduardo Enrique Castilla},
  journal={Birth defects research. Part A, Clinical and molecular teratology},
  year={2011},
  volume={91 9},
  pages={831-5}
}
BACKGROUND To assess spina bifida birth prevalence changes after folic acid fortification of wheat and maize flours began in Brazil in June 2004. METHODS Cross-sectional study of Brazilian live births in 2004 and 2006. Spina bifida birth prevalence from the Live Births Information System (SINASC: Sistema de Informações sobre Nascidos Vivos) in a prefortified period was compared to a period fortified with folic acid in each state. Observed prevalence rates in 2004 were used to calculate the… CONTINUE READING