Effects of folate in culture medium on common fragile sites in lymphocyte chromosomes from normal and leukemic children


The expression of common fragile sites at 69 bands was evaluated in 20 normal children and in 15 children with newly diagnosed acute leukemia using medium with folate (FA+) and without folate (FA-). As expected, the FA- medium significantly increased expression of aberrations in all study groups but the differences were larger for normal children than… (More)
DOI: 10.1007/BF00283720


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