Effects of focal frontal lesions on response inhibition.

  title={Effects of focal frontal lesions on response inhibition.},
  author={Terence W. Picton and Donald T. Stuss and Michael P. Alexander and Tim Shallice and Malcolm A. Binns and Susan Gillingham},
  journal={Cerebral cortex},
  volume={17 4},
This study examined the performance of 38 normal subjects and 43 patients with focal lesions of the frontal lobes on a simple go-nogo task where the probability of the nogo stimulus was either 75% or 25%. Patients with lesions to the superior medial parts of the frontal lobes, in particular to the left superior portion of Brodmann area 6 (which includes the supplementary motor areas and the premotor areas for the right hand) had an increased number of false alarms (incorrect responses to the… CONTINUE READING

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