Effects of fluoxetine and buspirone on the panicolytic-like response induced by the activation of 5-HT1A and 5-HT2A receptors in the rat dorsal periaqueductal gray

Abstract

Administration of 5-hydroxytryptamine (5-HT)1A and 5-HT2A receptor agonists into the dorsal periaqueductal gray (DPAG) inhibits escape, a defensive behavior associated with panic attacks. Long-term treatment with the antipanic compound imipramine enhances the DPAG 5-HT1A- and 5-HT2A-receptor-mediated inhibition of escape, implicating these receptors in the… (More)
DOI: 10.1007/s00213-005-0189-y

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@article{Bortoli2005EffectsOF, title={Effects of fluoxetine and buspirone on the panicolytic-like response induced by the activation of 5-HT1A and 5-HT2A receptors in the rat dorsal periaqueductal gray}, author={Valqu{\'i}ria Camin de Bortoli and Regina L{\'u}cia Nogueira and H{\'e}lio Zangrossi}, journal={Psychopharmacology}, year={2005}, volume={183}, pages={422-428} }