Effects of flumazenil in the treatment of benzodiazepine withdrawal – a double-blind pilot study

@article{Saxon1997EffectsOF,
  title={Effects of flumazenil in the treatment of benzodiazepine withdrawal – a double-blind pilot study},
  author={L. Saxon and P. Hjemdahl and A. Hiltunen and S. Borg},
  journal={Psychopharmacology},
  year={1997},
  volume={131},
  pages={153-160}
}
Abstract Flumazenil, a partial benzodiazepine agonist with low intrinsic activity, was tested for potential use in patients experiencing withdrawal symptoms after traditional treatment for benzodiazepine dependency. On two occasions, separated by 1–13 weeks, ten patients treated for benzodiazepine dependency and ten controls received cumulative doses of flumazenil (0.05, 0.10, 0.25, 0.50 and 1.00 mg at 15-min intervals) or placebo, with assessments of withdrawal symptoms and physiological… Expand
33 Citations

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