Effects of flecainide on exercise-induced ventricular arrhythmias and recurrences in genotype-negative patients with catecholaminergic polymorphic ventricular tachycardia.

@article{Watanabe2013EffectsOF,
  title={Effects of flecainide on exercise-induced ventricular arrhythmias and recurrences in genotype-negative patients with catecholaminergic polymorphic ventricular tachycardia.},
  author={Hiroshi Watanabe and Christian van der Werf and Ferran Ros{\'e}s-Noguer and Arnon Adler and Naokata Sumitomo and Christian Veltmann and Raphael Rosso and Zahurul A Bhuiyan and H. Bikker and Prince J. Kannankeril and Minoru Horie and Tohru Minamino and Sami Viskin and Bj{\"o}rn C Knollmann and John R. Till and Arthur A. M. Wilde},
  journal={Heart rhythm},
  year={2013},
  volume={10 4},
  pages={
          542-7
        }
}
BACKGROUND Conventional therapy with beta-blockers is incompletely effective in preventing arrhythmic events in patients with catecholaminergic polymorphic ventricular tachycardia (CPVT). We have previously discovered that flecainide in addition to conventional drug therapy prevents ventricular arrhythmias in patients with genotype-positive CPVT. OBJECTIVE To study the efficacy of flecainide in patients with genotype-negative CPVT. METHODS We studied the efficacy of flecainide for reducing… CONTINUE READING
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