Effects of flavonoids on α-glucosidase activity: potential targets for glucose homeostasis.

@article{Pereira2011EffectsOF,
  title={Effects of flavonoids on $\alpha$-glucosidase activity: potential targets for glucose homeostasis.},
  author={D. F. Pereira and L. H. Cazarolli and C. Lavado and Vanessa Mengatto and M. Figueiredo and A. Guedes and M. Pizzolatti and F. R. Silva},
  journal={Nutrition},
  year={2011},
  volume={27 11-12},
  pages={
          1161-7
        }
}
OBJECTIVE Flavonoids are naturally occurring compounds widely distributed in plants, which have hypoglycemic potential and have been described as glucosidase inhibitors. This study evaluated the effect of flavonoids on intestinal glucosidase activity after in vivo and in vitro treatment. METHODS For the in vivo studies animals received quercetin by gavage and for the in vitro assays a segment of the small intestine was used. To obtain the oral glucose tolerance curve fasted normal rats were… Expand
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