Effects of firocoxib and tepoxalin on healing in a canine gastric mucosal injury model.

@article{Goodman2009EffectsOF,
  title={Effects of firocoxib and tepoxalin on healing in a canine gastric mucosal injury model.},
  author={L. Goodman and B. Torres and J. Punke and L. Reynolds and A. Speas and A. Ellis and S. Budsberg},
  journal={Journal of veterinary internal medicine},
  year={2009},
  volume={23 1},
  pages={
          56-62
        }
}
  • L. Goodman, B. Torres, +4 authors S. Budsberg
  • Published 2009
  • Medicine
  • Journal of veterinary internal medicine
  • BACKGROUND Little is known about the effect of dual cyclooxygenase (COX) and lipoxygenase inhibition on canine gastric mucosal healing. OBJECTIVE This study compares the effects of putative dual COX and 5-lipoxygenase inhibition with that of COX-2 selective inhibition on gastric mucosal lesion healing in dogs. ANIMALS Six normal adult mixed-breed research dogs. METHODS Gastric body and pyloric lesions were induced by endoscopic biopsy. Dogs were treated with tepoxalin, firocoxib, or… CONTINUE READING
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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 43 REFERENCES
    Prostaglandins and leukotrienes: advances in eicosanoid biology.
    • 3,117
    • PDF