Effects of fifteen PBDE metabolites, DE71, DE79 and TBBPA on steroidogenesis in the H295R cell line.

  title={Effects of fifteen PBDE metabolites, DE71, DE79 and TBBPA on steroidogenesis in the H295R cell line.},
  author={Renfang Song and Yuhe He and Margaret Burkhardt Murphy and Leo Yeung and Richard Man Kit Yu and Michael Hon-Wah Lam and Paul K S Lam and Markus Hecker and John Paul Giesy and Rudolf Shiu Sun Wu and Wenbing Zhang and Guoying Sheng and Jiamo Fu},
  volume={71 10},
Polybrominated diphenyl ethers (PBDEs) and tetrabromobisphenol A (TBBPA) are brominated flame retardants that are produced in large quantities and are commonly used in construction materials, textiles, and as polymers in electronic equipment. Environmental and human levels of PBDEs have been increasing in the past 30 years, but the toxicity of PBDEs is not fully understood. Studies on their effects are relatively limited, and show that PBDEs are neurotoxins and potential endocrine disrupters… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 44 references

1888–1894 distribution and metabolic and hormonal activities in mice

R. Song
Chemosphere • 2008

Effects of twenty PBDE metabolites on steroidogenesis in the H 295 R cell line

M. Hecker, J. L. Newsted, +4 authors J. P. Giesy
Toxicol . Lett . • 2006
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