Effects of fibroblast-myocyte coupling on cardiac conduction and vulnerability to reentry: A computational study.

@article{Xie2009EffectsOF,
  title={Effects of fibroblast-myocyte coupling on cardiac conduction and vulnerability to reentry: A computational study.},
  author={Yuanfang Xie and Alan Garfinkel and Patrizia Camelliti and Peter Kohl and James N. Weiss and Zhilin Qu},
  journal={Heart rhythm},
  year={2009},
  volume={6 11},
  pages={1641-9}
}
BACKGROUND Recent experimental studies have documented that functional gap junctions form between fibroblasts and myocytes, raising the possibility that fibroblasts play roles in cardiac electrophysiology that extend beyond acting as passive electrical insulators. OBJECTIVE The purpose of this study was to use computational models to investigate how fibroblasts may affect cardiac conduction and vulnerability to reentry under different fibroblast-myocyte coupling conditions and tissue… CONTINUE READING

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