Effects of fibroblast growth factor 9 (FGF9) on steroidogenesis and gene expression and control of FGF9 mRNA in bovine granulosa cells.

@article{Schreiber2012EffectsOF,
  title={Effects of fibroblast growth factor 9 (FGF9) on steroidogenesis and gene expression and control of FGF9 mRNA in bovine granulosa cells.},
  author={N. B. Schreiber and L. Spicer},
  journal={Endocrinology},
  year={2012},
  volume={153 9},
  pages={
          4491-501
        }
}
  • N. B. Schreiber, L. Spicer
  • Published 2012
  • Biology, Medicine
  • Endocrinology
  • Gene expression of fibroblast growth factor-9 (FGF9) is decreased in granulosa cells (GC) of cystic follicles compared with normal dominant follicles in cattle. The objectives of this study were to investigate the effects of FGF9 on GC steroidogenesis, gene expression, and cell proliferation and to determine the hormonal control of GC FGF9 production. GC were collected from small (1-5 mm) and large (8-22 mm) bovine follicles and treated in vitro with various hormones in serum-free medium for 24… CONTINUE READING
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