Effects of fetuin on zona pellucida hardening and fertilizability of equine oocytes matured in vitro.

@article{Dellaquila1999EffectsOF,
  title={Effects of fetuin on zona pellucida hardening and fertilizability of equine oocytes matured in vitro.},
  author={Maria Elena Dell'aquila and Massimo De Felici and Serafina Massari and Filippo Maritato and Paolo Minoia},
  journal={Biology of reproduction},
  year={1999},
  volume={61 2},
  pages={533-40}
}
In vitro fertilization (IVF) has had poor success in the horse, a situation related to low rates of sperm penetration through the zona pellucida (ZP). Zona pellucida hardening (ZPH) is seen in mouse and rat oocytes cultured in serum-free medium. The hardened ZP is refractory to sperm penetration. Fetuin, a component of fetal calf serum, inhibits ZPH and allows normal fertilization rates in oocytes cultured in the absence of serum. We evaluated whether fetuin is present in horse serum and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

Similar Papers

Loading similar papers…