Effects of fetal cardiac anomalies on ductus venosus and aortic isthmus doppler profiles

  title={Effects of fetal cardiac anomalies on ductus venosus and aortic isthmus doppler profiles},
  author={G{\"u}lşah Ilhan and Ahmet Cem Iyibozkurt and Halil İbrahim Kalelioğlu and Lem’i Ibrahimoğlu and Ali Galip Zebitay and Meryem Kurek Eken and Ayşe Filiz G{\"o}kmen Karasu},
  journal={Archives of Gynecology and Obstetrics},
PurposeTo demonstrate the blood flow profiles of fetuses with cardiac anomalies at the level of Ductus venosus (DV) and Aortic isthmus (AI) to evaluate the effects of fetal cardiac anomalies on these profiles, and how these profile changes contribute to cardiac anomaly screening studies as a marker.MethodsDV and AI doppler studies were applied to 64 singleton pregnant women with fetal cardiac anomalies and 74 pregnant women with healthy fetuses. DV-PVIV (peak velocity index for veins) for DV… 
4 Citations
The Aortic Isthmus: A Significant yet Underexplored Watershed of the Fetal Circulation
The physiological origin of this Doppler waveform is outlined, the various published indices are described, the published literature to date is summarised, and potential future research and hopefully clinical applications are outlined.
Clinical Significance of Ductus Venosus Waveform as Generated by Pressure-volume Changes in the Fetal Heart
This review serves to improve the understanding of the mechanisms that regulate the blood flow redistribution between the fetal liver circulation and fetal heart and the clinical significance of the ductus venosus waveform as generated by pressure-volume changes in the fetal heart.
Reference Values and Z Scores for Pulsed-Wave Doppler and M-Mode Measurements in Fetal Echocardiography.
Retrograde flow in aortic isthmus in normal and fetal heart disease by principal component analysis and computational fluid dynamics
This study sought to investigate the relationship between RF and blood flow parameters, and develop a computational fluid dynamics (CFD) model to understand the mechanisms underlying this observation.


Ductus venosus flow velocities in relation to the cardiac defects in first-trimester fetuses with enlarged nuchal translucency.
Fetuses with NT >95th percentile and cardiac defects show markedly changed DV velocities because the type of cardiac defects cannot always explain the hemodynamic changes found in these fetuses, some other mechanisms seem to be involved.
The ductus venosus in early pregnancy and congenital anomalies
The ductus venosus is a tiny vessel leading oxygenated blood from the placenta to the fetal heart and its flow assessment has been used as an indicator of fetal acidemia, and early cardiac dysfunction, signaled by abnormal DV blood flow, was suggested as the underlying cause of increased nuchal translucency.
Ductus venosus index: a method for evaluating right ventricular preload in the second‐trimester fetus
  • G. Devore, J. Horenstein
  • Medicine
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
  • 1993
Two fetuses, one with pulmonary atresia and the second with severe cardiovascular dysfunction, demonstrated an abnormal ductus venosus index associated with absent flow velocity during atrial systole, associated with notching in the umbilical vein.
Quantitative Assessment of Circulatory Changes in the Fetal Aortic Isthmus During Progressive Increase of Resistance to Umbilical Blood Flow
Variations in Doppler blood flow velocity waveforms and integrals of the aortic isthmus can be used as a sensitive indicator of the state of the umbilical circulation.
Blood flow and the degree of shunting through the ductus venosus in the human fetus.
Correlation between prenatal velocity waveforms in the aortic isthmus and neurodevelopmental outcome between the ages of 2 and 4 years.
Measuring the ratio of antegrade to retrograde velocity integrals in the aortic isthmus could help in the indirect assessment of cerebral oxygenation during placental circulatory insufficiency.
Middle cerebral artery flow velocity waveforms in normal and small-for-gestational-age fetuses.
The Impact of Fetal Echocardiography
Fetal echocardiography has improved the understanding of the development and evolution of congenital heart disease in utero, and it may serve a role in identifying candidates for prenatal intervention.
The ductus venosus.
The present review relates to the modern concept of this vein predominantly founded on clinical studies, indicating that, during this period, the fetal liver has a higher priority than the shunting through the ductus venosus, apart from the compensatory redistribution needed during extreme challenges of placental compromize and hypoxemia.