Effects of fatty acids on invasion through reconstituted basement membrane ('Matrigel') by a human breast cancer cell line.

@article{Connolly1993EffectsOF,
  title={Effects of fatty acids on invasion through reconstituted basement membrane ('Matrigel') by a human breast cancer cell line.},
  author={Jeanne M. Connolly and David P. Rose},
  journal={Cancer letters},
  year={1993},
  volume={75 2},
  pages={137-42}
}
An in vitro invasion assay system was used to examine the effects of linoleic acid, an omega-6 fatty acid, and two omega-3 fatty acids, eicosapentaenoic acid and docosahexaenoic acid, on the invasive capacity of MDA-MB-435 human breast cancer cells. Linoleic acid stimulated, and the omega-3 fatty acids inhibited, tumor cell invasion at concentrations of 0.25 and 0.5 microgram/ml. Indomethacin, 20 micrograms/ml, completely suppressed the stimulatory activity of linoleic acid, suggesting that… CONTINUE READING

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An in vitro invasion assay system was used to examine the effects of linoleic acid , an omega-6 fatty acid , and two omega-3 fatty acids , eicosapentaenoic acid and docosahexaenoic acid , on the invasive capacity of MDA - MB-435 human breast cancer cells .
An in vitro invasion assay system was used to examine the effects of linoleic acid , an omega-6 fatty acid , and two omega-3 fatty acids , eicosapentaenoic acid and docosahexaenoic acid , on the invasive capacity of MDA - MB-435 human breast cancer cells .
An in vitro invasion assay system was used to examine the effects of linoleic acid , an omega-6 fatty acid , and two omega-3 fatty acids , eicosapentaenoic acid and docosahexaenoic acid , on the invasive capacity of MDA - MB-435 human breast cancer cells .
Effects of fatty acids on invasion through reconstituted basement membrane ( ' Matrigel ' ) by a human breast cancer cell line .
Indomethacin , 20 micrograms / ml , completely suppressed the stimulatory activity of linoleic acid , suggesting that these fatty acid effects are mediated via eicosanoid biosynthesis .
Indomethacin , 20 micrograms / ml , completely suppressed the stimulatory activity of linoleic acid , suggesting that these fatty acid effects are mediated via eicosanoid biosynthesis .
An in vitro invasion assay system was used to examine the effects of linoleic acid , an omega-6 fatty acid , and two omega-3 fatty acids , eicosapentaenoic acid and docosahexaenoic acid , on the invasive capacity of MDA - MB-435 human breast cancer cells .
An in vitro invasion assay system was used to examine the effects of linoleic acid , an omega-6 fatty acid , and two omega-3 fatty acids , eicosapentaenoic acid and docosahexaenoic acid , on the invasive capacity of MDA - MB-435 human breast cancer cells .
Linoleic acid stimulated , and the omega-3 fatty acids inhibited , tumor cell invasion at concentrations of 0.25 and 0.5 microgram / ml .
An in vitro invasion assay system was used to examine the effects of linoleic acid , an omega-6 fatty acid , and two omega-3 fatty acids , eicosapentaenoic acid and docosahexaenoic acid , on the invasive capacity of MDA - MB-435 human breast cancer cells .
Linoleic acid stimulated , and the omega-3 fatty acids inhibited , tumor cell invasion at concentrations of 0.25 and 0.5 microgram / ml .
An in vitro invasion assay system was used to examine the effects of linoleic acid , an omega-6 fatty acid , and two omega-3 fatty acids , eicosapentaenoic acid and docosahexaenoic acid , on the invasive capacity of MDA - MB-435 human breast cancer cells .
An in vitro invasion assay system was used to examine the effects of linoleic acid , an omega-6 fatty acid , and two omega-3 fatty acids , eicosapentaenoic acid and docosahexaenoic acid , on the invasive capacity of MDA - MB-435 human breast cancer cells .
An in vitro invasion assay system was used to examine the effects of linoleic acid , an omega-6 fatty acid , and two omega-3 fatty acids , eicosapentaenoic acid and docosahexaenoic acid , on the invasive capacity of MDA - MB-435 human breast cancer cells .
Linoleic acid stimulated , and the omega-3 fatty acids inhibited , tumor cell invasion at concentrations of 0.25 and 0.5 microgram / ml .
Effects of fatty acids on invasion through reconstituted basement membrane ( ' Matrigel ' ) by a human breast cancer cell line .
An in vitro invasion assay system was used to examine the effects of linoleic acid , an omega-6 fatty acid , and two omega-3 fatty acids , eicosapentaenoic acid and docosahexaenoic acid , on the invasive capacity of MDA - MB-435 human breast cancer cells .
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