Effects of fatty acid sucrose esters on ceftibuten transport by rat intestinal brush-border membrane vesicles.

@article{Koga1998EffectsOF,
  title={Effects of fatty acid sucrose esters on ceftibuten transport by rat intestinal brush-border membrane vesicles.},
  author={Kenjiro Koga and Masahiro Murakami and Susumu Kawashima},
  journal={Biological & pharmaceutical bulletin},
  year={1998},
  volume={21 7},
  pages={747-51}
}
The effects of fatty acid sucrose esters on membrane lipid dynamics and ceftibuten transport by rat intestinal brush-border membrane vesicles (BBMV) were examined to clarify the differences in the action of mono- and poly-acyl sucrose esters on the drug transport. Fatty acid sucrose mono-acyl ester (SS) inhibited ceftibuten transport by BBMV similar to the action of polyoxyethylene sorbitans (Tweens), while fatty acid sucrose polyacyl ester mixtures (F-160 and F-140) did not affect the drug… CONTINUE READING