Effects of fatty acid bile acid conjugates (FABACs) on biliary lithogenesis: potential consequences for non-surgical treatment of gallstones.

Abstract

Fatty acid bile acid conjugates (FABACs) are novel synthetic lipid molecules, which were designed for the treatment of cholesterol gallstones. The rationale was to combine a cholesterol solubilizing moiety (a saturated fatty acid) with a bile acid (cholic acid) as a vehicle to enable secretion into bile and entry into the enterohepatic circulation. An amide… (More)

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@article{Konikoff2005EffectsOF, title={Effects of fatty acid bile acid conjugates (FABACs) on biliary lithogenesis: potential consequences for non-surgical treatment of gallstones.}, author={Fred Meir Konikoff and Tuvia Gilat}, journal={Current drug targets. Immune, endocrine and metabolic disorders}, year={2005}, volume={5 2}, pages={171-5} }