Effects of family history and genetic polymorphism on the cost-effectiveness of chemoprevention with finasteride for prostate cancer.

@article{Reed2011EffectsOF,
  title={Effects of family history and genetic polymorphism on the cost-effectiveness of chemoprevention with finasteride for prostate cancer.},
  author={Shelby D Reed and Charles D. Scales and Suzanne Biehn Stewart and Jielin Sun and Judd W. Moul and Kevin A. Schulman and Jianfeng Xu},
  journal={The Journal of urology},
  year={2011},
  volume={185 3},
  pages={841-7}
}
PURPOSE Improvement in the cost-effectiveness of chemoprevention for prostate cancer could be realized through the identification of patients at higher risk. We estimated the cost-effectiveness of prostate cancer chemoprevention across risk groups defined by family history and number of risk alleles, and the cost-effectiveness of targeting chemoprevention to higher risk groups. MATERIALS AND METHODS We developed a probabilistic Markov model to estimate costs, survival and quality adjusted… CONTINUE READING

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