Effects of extracellular matrix on the expression of peroxisomes in primary rat hepatocyte cultures.

@article{Depreter2000EffectsOE,
  title={Effects of extracellular matrix on the expression of peroxisomes in primary rat hepatocyte cultures.},
  author={Marianne Depreter and Tom Tytgat and Sonja Beken and Marc F. A. Espeel and Karen De Smet and Vera Rogiers and Frank Roels},
  journal={Journal of hepatology},
  year={2000},
  volume={32 3},
  pages={381-91}
}
BACKGROUND/AIMS Peroxisomes in wild-type cells vary between tissues and developmental stages. In the liver of some peroxisomal deficiency disorder patients, rare parenchymal cells express normal peroxisomes (mosaics); the mechanism is unknown. Our aim was to find factors regulating peroxisome expression. METHODS Liver-specific as well as peroxisome characteristics were studied in three types of primary rat hepatocyte cultures. RESULTS Total glutathione S-transferase activity and albumin… CONTINUE READING