Effects of extracellular bicarbonate ions and pH on volume-regulatory taurine efflux from rat cerebral cortical slices in vitro: evidence for separate neutral and anionic transport mechanisms.


Net efflux of [3H]taurine from cells in pre-loaded slices of rat cerebral cortex has previously been shown to occur via an anionic pathway, believed to consist of exchange of anionic taurine for extracellular Cl-, and operating under both isomotic and hypoosmotic conditions, and a calmodulin-dependent mechanism, activated by hypoosmotic stress: the latter… (More)