Effects of extended-access self-administration and deprivation on breakpoints maintained by cocaine in rats

@article{Liu2004EffectsOE,
  title={Effects of extended-access self-administration and deprivation on breakpoints maintained by cocaine in rats},
  author={Y. Liu and D. C. Roberts and D. Morgan},
  journal={Psychopharmacology},
  year={2004},
  volume={179},
  pages={644-651}
}
  • Y. Liu, D. C. Roberts, D. Morgan
  • Published 2004
  • Medicine, Psychology
  • Psychopharmacology
  • RationaleAnimal models that identify the effects of self-administration histories on subsequent patterns, levels of intake, and other aspects of reinforcement will help clarify the controlling variables of human drug use.ObjectiveIdentify the effects of extended-access to cocaine and 1 or 7 days of deprivation on cocaine-maintained breakpoints on a progressive ratio (PR) schedule of reinforcement.MethodsMale, Sprague–Dawley rats were trained to self-administer intravenous cocaine (expt 1: 1.5… CONTINUE READING

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