Effects of exposure to polychlorinated biphenyls and organochlorine pesticides on thyroid function during pregnancy.

@article{Chevrier2008EffectsOE,
  title={Effects of exposure to polychlorinated biphenyls and organochlorine pesticides on thyroid function during pregnancy.},
  author={Jonathan Chevrier and Brenda Eskenazi and Nina T. Holland and A S A Bradman and Dana Boyd Barr},
  journal={American journal of epidemiology},
  year={2008},
  volume={168 3},
  pages={
          298-310
        }
}
In this study, the authors' objective was to determine whether serum concentrations of polychlorinated biphenyls (PCBs), hexachlorobenzene, p,p'-dichlorodiphenyl trichloroethane (DDT), o,p'-DDT, and p,p'-dichlorodiphenyl dichloroethylene (DDE) are associated with thyroid function during pregnancy. These compounds, as well as thyroid-stimulating hormone, total thyroxine, and free thyroxine, were measured in serum samples collected between October 1999 and October 2000 from 334 pregnant women… Expand
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Organochlorine compounds, iodine intake, and thyroid hormone levels during pregnancy.
TLDR
It is indicated that exposure to OCs during pregnancy can alter TH levels, especially for PCBs and total T3 (p-value for the interaction between cohorts >0.8). Expand
Environmental exposure to organochlorine pesticides and deficits in cochlear status in children
TLDR
Exposure to OCPs in infancy at environmental concentrations may be associated with hearing deficits and tonotopicity in the association of pesticides with amplitude of DPOAEs was observed as its strength was frequency dependent. Expand
Association between thyroid hormone levels and 4,4'-DDE concentrations in pregnant women (Valencia, Spain).
TLDR
Serum concentrations of 4,4'-DDE were associated with increased TSH and reduced FT4 but not TT3 levels, suggesting that some environmental chemicals may interfere with the thyroid system of pregnant women. Expand
Assessment of polychlorinated biphenyl congeners, thyroid stimulating hormone, and free thyroxine among New York state anglers.
TLDR
The results of this study suggest that Lake Ontario sportfish consumers may comprise a high risk population for PCB related thyroid function alteration and warrant a larger confirmatory investigation. Expand
Prenatal exposure to organochlorine compounds and neonatal thyroid stimulating hormone levels
TLDR
Prenatal exposure to β-HCH may affect neonatal thyroid hormone status and its function in neurological development, and associations between neonatal TSH levels and prenatal OC exposure adjusted for covariates were assessed. Expand
Association between several persistent organic pollutants and thyroid hormone levels in serum among the pregnant women of Korea.
TLDR
The thyroid hormone levels of all subjects were within the reference range, however exposure to several target POPs were clearly related with potential for disrupting thyroid hormone balance among pregnant women, at the current level of exposure. Expand
Serum dioxin concentrations and thyroid hormone levels in the Seveso Women's Health Study.
TLDR
TCDD exposure, particularly exposure before menarche, may have enduring impacts on women's total thyroxine levels, and initial exposure appears to be more influential than remaining body burden. Expand
Thyroid Hormone Levels of Pregnant Inuit Women and Their Infants Exposed to Environmental Contaminants
TLDR
There is little evidence that the environmental contaminants analyzed in this study affect thyroid hormone status in Inuit mothers and their infants within the first year of life. Expand
Environmental pollutants and the thyroid.
TLDR
Isoflavones inhibit thyroperoxidase (TPO) activity, and, therefore, may cause goitre and hypothyroidism if ingested at high levels, particularly in iodine-deficient individuals. Expand
Long-term exposure to organochlorine pesticides and thyroid status in adults in a heavily contaminated area in Brazil.
TLDR
It is suggested that OC pesticides can affect the thyroid system through gender-specific mechanisms that may differ among compounds, and further detailed investigations and health monitoring should be warranted for this population. Expand
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References

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TLDR
A significant negative correlation between maternal total triiodothyronine levels and three non-coplanar congeners, three pesticides, and inorganic Hg in healthy women recruited during pregnancy is found. Expand
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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