Effects of exogenous prostaglandins on aqueous humor dynamics and blood-aqueous barrier function.

@article{Toris1997EffectsOE,
  title={Effects of exogenous prostaglandins on aqueous humor dynamics and blood-aqueous barrier function.},
  author={Carol B. Toris and Carl B. Camras and Michael E Yablonski and Richard F. Brubaker},
  journal={Survey of ophthalmology},
  year={1997},
  volume={41 Suppl 2},
  pages={S69-75}
}
Topical prostaglandins (PGs) are very effective at reducing intraocular pressure (IOP) in a variety of animals and in humans with relatively few side effects. The mechanisms of action of several PGs, their prodrugs and analogues have been studied in rabbits, cats, monkeys and humans. PGF2 alpha and its analogues evaluated in monkeys include PGF2 alpha-tromethamine salt, PGF2 alpha -isopropylester (-IE), S-1033, PhXA34, PhDH100A and latanoprost (PhXA41). Aqueous flow and outflow facility are… CONTINUE READING

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