Effects of exogenous neuropeptide Y on automaticity of isolated Purkinje fibers and atrium.

@article{Sosunov1996EffectsOE,
  title={Effects of exogenous neuropeptide Y on automaticity of isolated Purkinje fibers and atrium.},
  author={Eugene A. Sosunov and Evgeny P. Anyukhovsky and Michael R. Rosen},
  journal={Journal of molecular and cellular cardiology},
  year={1996},
  volume={28 5},
  pages={967-75}
}
Neuropeptide Y exerts prejunctional effects on automaticity in cardiac pacemaker tissue and postjunctional effects on contractile activity of cardiomyocytes. It is uncertain whether neuropeptide Y has postjunctional effects on cardiac automaticity. This paper reports a study of the actions of exogenous neuropeptide Y (10(-10)-10(-6) M) on automaticity of isolated preparations of canine Purkinje fibers and guinea-pig right atrium. Neuropeptide Y had no effect on the rate of normal and abnormal… CONTINUE READING