Effects of excitotoxic lesions of the basal forebrain on MFB self-stimulation.

  title={Effects of excitotoxic lesions of the basal forebrain on MFB self-stimulation.},
  author={Andreas Arvanitogiannis and Meg A Waraczynski and Peter Shizgal},
  journal={Physiology & behavior},
  volume={59 4-5},
Electrolytic lesions of the anterior medial forebrain bundle (MFB) have been shown to attenuate the rewarding impact of stimulating more caudal MFB sites. In the present study, excitotoxic lesions were employed to determine the relative contribution of somata or fibers of passage contributing to that effect. Changes in reward efficacy were inferred, at three currents, from lateral displacements of the curve relating the rate of responding to the number of stimulation pulses per train. After… CONTINUE READING


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