Effects of excitatory amino acids on the hypothalamic-pituitary-adrenal axis of the neonatal rat.

Abstract

Most stimuli that elicit a response by the hypothalamic-pituitary-adrenal (HPA) axis of adult rats fail to do so in infant rats aged 4-14 postnatal days (pnd). This interval is termed the stress hyporesponsive period (SHRP). The present study examined the development of the HPA response to the excitatory amino acids (EAAs), N-methyl-D-aspartic acid (NMDA… (More)

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