Effects of evening vs morning thyroxine ingestion on serum thyroid hormone profiles in hypothyroid patients.


OBJECTIVE Standard drug information resources recommend that l-thyroxine be taken half an hour before breakfast on an empty stomach, to prevent interference of its intestinal uptake by food or medication. We observed cases in which TSH levels improved markedly after changing the administration time of l-thyroxine to the late evening. We therefore conducted… (More)


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