Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet.

@article{Schwartz2007EffectsOE,
  title={Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet.},
  author={Jules I. Schwartz and Chau T. Thach and Kenneth C. Lasseter and Jutta L Miller and David Hreniuk and Deborah A Hilliard and Karen M Snyder and Barry J. Gertz and Keith M. Gottesdiener},
  journal={Journal of clinical pharmacology},
  year={2007},
  volume={47 12},
  pages={1521-31}
}
This multicenter, double-blind, randomized, placebo-controlled, parallel-group study assessed renal function during dosing with etoricoxib 90 mg daily, celecoxib 200 mg twice daily, and naproxen 500 mg twice daily. Male and female subjects 60 to 81 years old (n = 85), in sodium balance on a controlled, normal sodium diet, were treated for 15 days. There were no clinically meaningful between-treatment differences in urinary sodium excretion, creatinine clearance, body weight, or serum… CONTINUE READING