Effects of ethanol on mouse embryonic stem cells.

  title={Effects of ethanol on mouse embryonic stem cells.},
  author={Alla Arzumnayan and Helen Anni and Raphael Rubin and Emanuel Rubin},
  journal={Alcoholism, clinical and experimental research},
  volume={33 12},
BACKGROUND Fetal alcohol syndrome (FAS) reflects a constellation of congenital abnormalities caused by excess maternal consumption of alcohol. It is likely that interference with embryonic development plays a role in the pathogenesis of the disorder. Ethanol-induced apoptosis has been suggested as a causal factor in the genesis of FAS. Mouse embryonic stem (mES) cells are pluripotent cells that differentiate in vitro to cell aggregates termed embryoid bodies (EBs), wherein differentiation… CONTINUE READING
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