Effects of ethanol on glycoprotein synthesis and secretion during inflammation-induced stimulation of hepatic glycoprotein secretion.

@article{Tuma1982EffectsOE,
  title={Effects of ethanol on glycoprotein synthesis and secretion during inflammation-induced stimulation of hepatic glycoprotein secretion.},
  author={D. Tuma and M. F. Sorrell},
  journal={Toxicology and applied pharmacology},
  year={1982},
  volume={63 2},
  pages={
          303-11
        }
}
  • D. Tuma, M. F. Sorrell
  • Published 1982
  • Chemistry, Medicine
  • Toxicology and applied pharmacology
  • Abstract The effects of ethanol on glycoprotein metabolism in liver slices obtained from rats whose synthesis and secretion of glycoproteins had been stimulated by turpentine-induced inflammation were investigated and compared to colchicine, a potent inhibitor of secretion. Inflammation resulted in a large stimulation in liver slices of [ 14 C]glucosamine and [ 14 C]leucine incorporation into medium proteins and a lesser stimulation into hepatocellular proteins. Both ethanol (10 m m ) and… CONTINUE READING

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