Effects of ethanol exposure during the third trimester equivalent on neuron number in rat hippocampus and dentate gyrus.

@article{West1986EffectsOE,
  title={Effects of ethanol exposure during the third trimester equivalent on neuron number in rat hippocampus and dentate gyrus.},
  author={James R. West and Kristin Hamre and Martin D. Cassell},
  journal={Alcoholism, clinical and experimental research},
  year={1986},
  volume={10 2},
  pages={190-7}
}
An artificial rearing procedure was used to expose neonatal rats to a formula containing 3.74% ethanol during postnatal days 4 through 10. This treatment produced a mean blood ethanol concentration of 379.8 +/- 17.3 mg/dl. When the pups were killed on the afternoon of postnatal day 10, brain weight to body weight ratio in the ethanol-exposed rats was reduced 22.4% and 21.5% compared to suckle and pair-fed controls, respectively. Ethanol exposure also resulted in a 16% reduction of neurons in… CONTINUE READING

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