Effects of ethanol, potassium metabisulfite, formaldehyde and hydrogen peroxide on gastric carcinogenesis in rats after initiation with N-methyl-N'-nitro-N-nitrosoguanidine.

@article{Takahashi1986EffectsOE,
  title={Effects of ethanol, potassium metabisulfite, formaldehyde and hydrogen peroxide on gastric carcinogenesis in rats after initiation with N-methyl-N'-nitro-N-nitrosoguanidine.},
  author={Masakazu Takahashi and Ryohei P. Hasegawa and Fumio Furukawa and Kazuhiro Toyoda and Hidetaka Sato and Yuzo Hayashi},
  journal={Japanese journal of cancer research : Gann},
  year={1986},
  volume={77 2},
  pages={118-24}
}
Ethanol, potassium metabisulfite, formaldehyde and hydrogen peroxide were tested for tumor-promoting activity in a two-stage stomach carcinogenesis experiment. Male outbred Wistar rats were given N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in the drinking water (100 mg/liter) and a diet supplemented with 10% sodium chloride for 8 weeks. Thereafter, they were maintained on drinking water containing either 10% ethanol, 1% potassium metabisulfite, 0.5% formalin (formaldehyde) or 1% hydrogen… CONTINUE READING
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