Effects of estrous cycle stage and pregnancy on follistatin gene expression and immunoreactivity in rat reproductive tissues: progesterone is implicated in regulating uterine gene expression.

@article{Mercado1993EffectsOE,
  title={Effects of estrous cycle stage and pregnancy on follistatin gene expression and immunoreactivity in rat reproductive tissues: progesterone is implicated in regulating uterine gene expression.},
  author={Melissa M. Mercado and Shunichi Shimasaki and Nicholas Chi-Kwan Ling and L V Depaolo},
  journal={Endocrinology},
  year={1993},
  volume={132 4},
  pages={
          1774-81
        }
}
Follistatin, a monomeric protein originally isolated from ovarian follicular fluid, is now believed to be a major local regulator of the multifaceted actions of activin by virtue of its activin-binding properties. In view of the ability of follistatin to stimulate progesterone production from granulosa cells and its presence in newly formed corpora lutea, the following study was conducted to determine the effects of cycle stage and pregnancy on follistatin gene expression and immunoreactivity… CONTINUE READING
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Alteration in follistatin gene expression detected in prenatally androgenized rats.

  • Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
  • 2017

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