Effects of estragole on the compound action potential of the rat sciatic nerve.

@article{LealCardoso2004EffectsOE,
  title={Effects of estragole on the compound action potential of the rat sciatic nerve.},
  author={J. H. Leal-Cardoso and B G Matos-Brito and J E G Lopes-Junior and K. V. Viana-Cardoso and A B Sampaio-Freitas and R O Brasil and Andrelina Noronha Coelho-de-Souza and A. A. Albuquerque},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2004},
  volume={37 8},
  pages={1193-8}
}
Estragole, a relatively nontoxic terpenoid ether, is an important constituent of many essential oils with widespread applications in folk medicine and aromatherapy and known to have potent local anesthetic activity. We investigated the effects of estragole on the compound action potential (CAP) of the rat sciatic nerve. The experiments were carried out on sciatic nerves dissected from Wistar rats. Nerves, mounted in a moist chamber, were stimulated at a frequency of 0.2 Hz, with electric pulses… CONTINUE READING

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