Effects of estradiol on liver estrogen receptor-alpha and its mRNA expression in hepatic fibrosis in rats.

@article{Xu2004EffectsOE,
  title={Effects of estradiol on liver estrogen receptor-alpha and its mRNA expression in hepatic fibrosis in rats.},
  author={J Xu and Jun Gong and Xin-ming Chang and Jin-yan Luo and Lei Dong and A B Renyong Jia and Gui-ping Xu},
  journal={World journal of gastroenterology},
  year={2004},
  volume={10 2},
  pages={250-4}
}
AIM Estradiol treatment regulates estrogen receptor (ER) level in normal rat liver. However, little information is available concerning the role of estrogen in regulating liver ER in hepatic fibrosis in rats. The present study was conducted to determine whether estradiol treatment in CCl4-induced liver fibrosis of female and ovariectomized rats altered liver ERalpha and its mRNA expression, and to investigate the possible mechanisms. METHODS Seventy female rats were divided into seven groups… CONTINUE READING
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