Effects of erythropoietin on ICAM-1 and PECAM-1 expressions on human umbilical vein endothelial cells subjected to oxidative stress.

@article{Kamianowska2011EffectsOE,
  title={Effects of erythropoietin on ICAM-1 and PECAM-1 expressions on human umbilical vein endothelial cells subjected to oxidative stress.},
  author={Monika Kamianowska and Marek Szczepański and Elżbieta Skrzydlewska},
  journal={Cell biochemistry and function},
  year={2011},
  volume={29 6},
  pages={437-41}
}
The protective effect of erythropoietin (Epo) is based on its ability to reduce oxidation and to stabilize the cells. The aim of the study was to evaluate the influence of Epo on malonyl dialdehyde (MDA), intercellular adhesion molecule-1 (ICAM-1) (CD54) and platelet-endothelial cell adhesion molecule-1 (PECAM-1) (CD31) levels on human umbilical vein endothelial cells (HUVECs) stimulated by tumour necrosis factor-α (TNF-α). HUVECs were incubated with Epo (10-40 IU ml⁻¹) or TNF-α (10-40 ng ml… CONTINUE READING
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